Market Watch57% of the early bets are on the Chargers.
Buffalo will be tough at home and they are playing with house money now that they are at the top of the division. Watkins looks great, EJ Manual is managing the game as required, and the defense hasn't slipped as much as people expected. Will it all translate into a 3-0 start to the season? I'm willing to bet against it. This will be their toughest test yet.
NFL Pick: SD +1.
Read more: Week 3 picks