It's shaping up to be a less profitable NFLX than the last two years, but the most important thing is not to start the season at a significant deficit. Week 4 is made up of largely backups (unless you're St Louis), so picks might not come until the final 24 hours before kickoff as we wait for information from coaches.
I'll be rolling out the rest of my Week 1 picks soon. After training camps and three weeks of the preseason I have a pretty good grasp on who I like and don't like heading into the season. The Week 1 lines are pretty sharp as is given how long people have had to pound them into shape, but I still see potential value on the board. I'll also have updated power rankings posted this week as well.